منابع مشابه
New inhalation devices.
ll is now accepted that inhaled bronchodilator therapy is, whenever possible, to be preferred to oral treatment in the routine management of reversible airflow obstruction [1). However, during the last two decades we have repeatedly been reminded that many patients have great difficulty in using the conventional pressurized metered dose inhaler (MDI) [2-6], today's most frequently prescribed in...
متن کاملInhalation drug delivery devices: technology update
The pulmonary route of administration has proven to be effective in local and systemic delivery of miscellaneous drugs and biopharmaceuticals to treat pulmonary and non-pulmonary diseases. A successful pulmonary administration requires a harmonic interaction between the drug formulation, the inhaler device, and the patient. However, the biggest single problem that accounts for the lack of desir...
متن کاملThe ADMIT series - issues in inhalation therapy. 6) Training tools for inhalation devices.
Inhaled medications are the preferred therapies for patients with asthma and COPD, but their effectiveness is limited by the patient's ability to use the device properly, an issue often neglected when these medications are prescribed. Correct inhaler technique must be taught and learnt, and requires educational and motivational programs aimed at patients and healthcare providers alike. Written ...
متن کاملPeripheral deposition of alpha1-protease inhibitor using commercial inhalation devices.
Patients with hereditary alpha1-proteinase inhibitor (alpha1-PI) deficiency are at risk of developing lung emphysema. To prevent the development of this disease, alpha1-PI replacement therapy via inhalation may be a more convenient and effective therapy than the intravenous administration of the drug. In order to optimise this treatment approach, lung deposition of inhaled radiolabelled alpha1-...
متن کاملRelative bioavailability of salbutamol to the lung following inhalation using metered dose inhalation methods and spacer devices.
BACKGROUND Inhalation aids do not require coordination between actuation of a metered dose inhaler (MDI) with inspiration and reduce oropharyngeal impaction. The delivery of salbutamol to the lung and systemic availability following inhalation with three commonly used spacers and an open mouth technique have been evaluated using a simple noninvasive technique based on urinary excretion 30 minut...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Canadian Respiratory Journal
سال: 2018
ISSN: 1198-2241,1916-7245
DOI: 10.1155/2018/5642074